Epigenetic Age Determination

While your genes are fixed, how they function is influenced by lifestyle and environment—these changes are called epigenetics.

Epigenetic analysis shows how habits (nutrition, stress, smoking) affect gene activation and reveals your biological age.

What Does It Mean?

• Using methylation data, biological age is calculated independent of chronological age; deviations (fast/slow aging) are detected.
• These deviations reflect how lifestyle or environmental exposures impact you at the cellular level.

Scientific Infrastructure: New Generation Biological Clocks

• GrimAge (Health Risk Clock): Highly predicts mortality risk and future health status.
• PhenoAge (Physiological Health Clock): Focuses on "phenotypic" age reflected in blood biochemistry.
• DunedinPACE (Aging Speedometer): Shows how fast you are biologically aging right now.

References

• Wang, Y. et al. (2022). Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores. Annual review of biomedical data science, 5.
• Lu, A. T., et al. (2019). DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY).
• Belsky, D. W., et al. (2022). DunedinPACE, a DNA methylation biomarker of the pace of aging. eLife.